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Perinatal Hepatitis B

Hepatitis B virus (HBV) infection in a pregnant woman poses a serious risk to her infant at birth. Without postexposure immunoprophylaxis, approximately 40% of infants born to HBV-infected mothers in the United States will develop chronic HBV infection, approximately one-fourth of whom will eventually die from chronic liver disease.

Perinatal HBV transmission can be prevented by identifying HBV-infected (i.e., Hepatitis B surface antigen [HBsAg]-positive) pregnant women and providing Hepatitis B immune globulin and Hepatitis B vaccine to their infants within 12 hours of birth.

Preventing perinatal HBV transmission is an integral part of the national strategy to eliminate Hepatitis B in the United States. National guidelines call for the following:

  • Universal screening of pregnant women for HBsAg during each pregnancy
  • Case management of HBsAg-positive mothers and their infants
  • Provision of immunoprophylaxis for infants born to infected mothers, including Hepatitis B vaccine and Hepatitis B immune globulin
  • Routine vaccination of all infants with the Hepatitis B vaccine series, with the first dose administered at birth

The Perinatal Hepatitis B Prevention Program is funded through the CDC’s National Center for Immunization and Respiratory Disease, Immunization Services Division, with technical support from CDC’s National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention. Since 1991, every state has received federal funding to support the Perinatal Hepatitis B Prevention Program.

Please click on the following links to find audience specific materials on perinatal hepatitis B:

Information for Pregnant Women & Mothers

Information for Prenatal Care Providers

Information for Hospitals & Birth Clerks

Information for Pediatric Providers

Additional Resources


Contact the Georgia Perinatal Hepatitis B Prevention Program:

Georgia Department of Public Health
Perinatal Hepatitis B Prevention Program
2 Peachtree Street NW, Suite 14-263  
Atlanta, GA 30303

Phone:  (404) 651-5196

Fax:  (404) 657-6871

 

 

 

 

 

Information for Pregnant Women & Mothers

Hepatitis B & Moms-to-Be (Pamphlet)  
Pamphlet gives detailed information about hepatitis B infection during pregnancy and the steps to protecting infants.  The pamphlet is available in mutiple languages.  Courtesy of the Asian Liver Center at Stanford University.

Protect Your Baby for Life (Pamphlet) 
Pamphlet answers many of the common questions asked by hepatitis B-infected pregnant women. Courtesy of the Centers for Disease Control and Prevention.

Brief Introduction to Hepatitis B for Parents of Adopted Children 
Information for parents who have adopted children that were born outside the US and their potential risk of hepatitis B infection. Courtesy of the Immunization Action Coalition.

2014 Recommended Immunizations for Children from Birth Through 6 Years Old 
An easy to read immunization schedule for parents that indicate what specific immunizations are due from birth to 6 years of age. Courtesy of the Centers for Disease Control and Prevention.

Hepatitis B Vaccine Information Sheet 
Hepatitis B disease and vaccine information for the public and health professionals. Courtesy of the Centers for Disease Control and Prevention. 

Find your local health department
Listing of all Georgia Health Departments, by county. Services include vaccination and testing.

 

 

 

 

 

Information for Prenatal Care Providers

Testing for Hepatitis B Virus Infection During Pregnancy Flowchart for Prenatal Providers 
Flowchart for hepatitis B Infection testing during pregnancy.  Courtesy of the Centers for Disease Control and Prevention.

Interpretation of Hepatitis B Serologic Test Results 
Guide to interpreting and understanding hepatitis B serologic test results.  Courtesy of the Centers for Disease Control and Prevention.

Notifiable Disease Reporting Information
Guide for reporting notifiable diseases to the Georgia Department of Public Health. Includes list of notifiable diseases, case report form and contact information for county health departments.

Hepatitis B Vaccine Information Sheet 
Hepatitis B disease and vaccine information for the public and health professionals. Courtesy of the Centers for Disease Control and Prevention.

A Comprehensive Immunization Strategy to Eliminate Transmission of Hepatitis B Virus Infection in the United States 
Morbidity & Mortality Weekly Report from CDC that gives a comprehensive approach to preventing HBV transmission.  Courtesy of the Centers for Disease and Prevention.

A Pediatric Guide: Caring for Infants Born to Hepatitis B Infected Mothers
Quick reference poster that describes hepatitis B vaccination and testing for high-risk infants. The target audience for this publication is pediatric medical care providers. Developed by the Georgia Department of Public Health’s Perinatal Hepatitis B Prevention Program.

 

 

 

 

 

Information for Hospitals & Birth Clerks

Hepatitis B:  What Hospitals Need to Do to Protect Newborns 
Endorsed by AAFP, AAP, ACOG, and CDC, the Immunization Action Coalition's (IAC) comprehensive guidebook Hepatitis B: What Hospitals Need to Do to Protect Newborns is a complete resource for helping hospitals and birthing centers establish, implement, and optimize their birth dose policies. The book breaks new ground as a policy and best practices guide for newborn hepatitis B immunization.  Courtesy of the Immunization Action Coalition.

Procedures to Prevent Perinatal Hepatitis B Virus Transmission at Delivery – HBsAg Lab Report Available 
Algorithm for triaging infants born to women with reactive hepatitis B surface antigen (HBsAg) lab results. Courtesy of the Centers for Disease Control and Prevention.

Procedures to Prevent Perinatal Hepatitis B Virus Transmission at Delivery – HBsAg Lab Report Unavailable 
Algorithm for triaging infants born to women with unknown hepatitis B surface antigen (HBsAg) lab results. Courtesy of the Centers for Disease Control and Prevention

Interpretation of Hepatitis B Serologic Test Results 
Guide to interpreting and understanding hepatitis B serologic test results. Courtesy of the Centers for Disease Control and Prevention.

A Pediatric Guide: Caring for Infants Born to Hepatitis B Infected Mothers (Poster)
Quick reference poster that describes hepatitis B vaccination and testing for high-risk infants. The target audience for this publication is pediatric medical care providers. Developed by the Georgia Department of Public Health’s Perinatal Hepatitis B Prevention Program.

Sample of Admission orders for Labor and Delivery 
This is a sample of what hospital L&D units should include in their policy to prevent perinatal transmission of hepatitis B virus.  Courtesy of the Immunization Action Coalition.

Give the Birth Dose…Hepatitis B vaccine at birth saves lives 
Information on the importance of administering the hepatitis B birth dose. Courtesy of the Immunization Action Coalition.

Hepatitis B Vaccine Information Sheet
Hepatitis B disease and vaccine information for the public and health professionals. Courtesy of the Centers for Disease Control and Prevention.

A Comprehensive Immunization Strategy to Eliminate Transmission of Hepatitis B Virus Infection in the United States
Morbidity & Mortality Weekly Report from CDC that gives a comprehensive approach to preventing HBV transmission. Courtesy of the Centers for Disease and Prevention.

Notifiable Disease Reporting Information
Guide for reporting notifiable diseases to the Georgia Department of Public Health. Includes list of notifiable diseases, case report form and contact information for county health departments.

A Provider’s Guide for Entering HBIG and Hepatitis B Vaccine into the Georgia Vital Events Information System (VEIS) 
Quick reference guide for birth clerks who use the VEIS system in Georgia. This provides step-by-step guidance for completing the hepatitis B vaccination section of the birth worksheet.  Developed by the Georgia Department of Public Health’s Perinatal Hepatitis B Prevention Program.

Immunization Action Coalition's Hepatitis B Birth Dose Honor Roll
The Immunization Action Coalition (IAC) is recognizing hospitals and birthing centers that have attained 90% or greater coverage rates for administering hepatitis B vaccine at birth and have written policies aimed at protecting newborns.  Facilities that meet these criteria can apply to IAC’s national Hepatitis B Birth Dose Honor Roll. 

Click here to apply for IAC's Hepatitis B Birth Dose Honor Roll

 

 

 

 

 

 

Information for Pediatric Providers

A Pediatric Guide: Caring for Infants Born to Hepatitis B Infected Mothers
Quick reference poster that describes hepatitis B vaccination and testing for high-risk infants. The target audience for this publication is pediatric medical care providers. Developed by the Georgia Department of Public Health’s Perinatal Hepatitis B Prevention Program.

Hepatitis B Vaccine Information Sheet
Hepatitis B disease and vaccine information for the public and health professionals. Courtesy of the Centers for Disease Control and Prevention.

A Comprehensive Immunization Strategy to Eliminate Transmission of Hepatitis B Virus Infection in the United States
Morbidity & Mortality Weekly Report from CDC that gives a comprehensive approach to preventing HBV transmission. Courtesy of the Centers for Disease and Prevention

Notifiable Disease Reporting Information
Guide for reporting notifiable diseases to the Georgia Department of Public Health. Includes list of notifiable diseases, case report form and contact information for county health departments

 

 

 

 

 

Additional Resources

Georgia Department of Health: Viral Hepatitis
Website dedicated to viral hepatitis in Georgia.  Educational resources are available.

Centers for Disease Control and Prevention
Link to educational materials written by the CDC’s Division of Viral Hepatitis for mothers and parents of children that will be or have been exposed to hepatitis B.

HepB Moms
Resource for hepatitis B positive women. Materials are available in multiple languages.

Immunization Action Coalition
Website for both providers and parents regarding perinatal hepatitis B prevention and hepatitis B vaccine.

Hepatitis B Foundation
This nonprofit hepatitis B website addresses commonly asked questions concerning hepatitis B.

Asian Liver Foundation
Nonprofit hepatitis B foundation that addresses HBV in the Asian community.

State Electronic Notifiable Disease Surveillance System (SENDSS)

 

Georgia Registry of Immunization Transactions and Services (GRITS)