Arbrine and Ricinine (ABRC) in Urine

Brief Description

This method is a quantitative procedure for the measurement of Ricinine and L-Abrine in urine samples. The method uses Solid Phase Extraction (SPE) sample preparation and isotopically labeled internal standards for each analyte.

Laboratory Unit

Chemical Threat

Methodology

LC-MS/MS

Specimen Collection

Urine:

Collect ≥5.0 mL of urine. Two empty containers of the same lot number should be submitted with the specimen. 

Storage/Transport

Consultation is required with GPHL Emergency Response Coordinator Req 24/7 contact number: 866-782-4584.

Urine  should be stored frozen (-20°C or colder) and shipped with dry ice.

• FRM-QA 4 Refrigeration Outfit Guide

Acceptable Specimen Type(s)

Urine

Test Request

• GPHL Apollo Web Portal
• Web Portal Instructions
• For manual orders, download the GPHL Submission Form

Possible Results

• L-Abrine 5.0 µg/L – 500 µg/L
• Ricinine 0.3 µg/L –300 µg/L
• Not detected
• Unsatisfactory

Reference Range

Not detected

Unacceptable Conditions

• Missing testing requisition
• Missing minimum of 2 patient identifiers
• Improper labeling
• Specimen damaged, broken, or leaked in transit
• Improper storage/transport of specimen
• No specimen received (empty collection tube).
• Wrong specimen type
• Low volume (< 1.5 mL)
• Failure to keep specimen frozen

Interfering Substances

N/A

Result Reported

1-3 business days

Turnaround times may be affected by the scale of the event.

Fees

No charge

LOINC/Order Codes

54932-9 (Order code: CT031300)

Additional Information

N/A