Eastern Equine Encephalitis IgM 

Brief Description

The EEE MIA procedure is a replacement for the EEE MAC-ELISAs test with a single, equally sensitive, faster test. It is an immunological capture assay for the qualitative determination of IgM-class antibodies to the EEE virus.   

Laboratory Unit



Microsphere-based immunologic assay (MIA) 

Specimen Collection

  • Serum:
    • Collect in gold top SST tube, centrifuge
    • Collect in tiger top SST tube, centrifuge
  • Cerebral Spinal Fluid (CSF): 
    • Collect in a sterile container. 


  • Serum separated from the clot can be maintained at refrigerated temperature (2-8°C) during transit for no more than four days after collection. 
  • Serum separated from the clot can be aliquoted, stored frozen (-20°C or colder) and shipped with dry ice.
  • Cerebrospinal fluid should be stored frozen (-20°C or colder) and shipped with dry ice.
  • FRM-QA 4 Refrigeration Outfit Guide

Acceptable Specimen Type(s)


Cerebrospinal Fluid (CSF) 

Test Request

Possible Results

  • Positive
  • Negative
  • Unsatisfactory

Reference Range


Unacceptable Conditions

  • Missing testing requisition  
  • Missing minimum of 2 patient identifiers 
  • Improper labeling 
  • Improper storage/transport of specimen 
  • No specimen received (empty collection tube). 
  • Wrong specimen type 
  • Specimens damaged, broken, or leaking upon arrival 
  • Specimen grossly hemolyzed, lipemic, turbid, or contaminated  

Interfering Substances


Result Reported

5-7 business days, same day


No charge

LOINC/Order Codes

23046-6 (Order code: 16200)