Hepatitis B Anti-CORE

Brief Description

The LIAISON® XL Anti-HBc assay is an in vitro chemiluminescent immunoassay (CLIA) for the qualitative detection of IgG and IgM (total) antibodies to hepatitis B core antigen (anti-HBc) in human serum on the LIAISON® XL Analyzer. Assay results in conjunction with other laboratory results and clinical information may be used as an aid in the diagnosis of hepatitis B virus (HBV) infection in patients with symptoms of hepatitis or who may be at risk for HBV infection.

Laboratory Unit



Chemiluminescence Immunoassay (CLIA)

Specimen Collection


Collect in gold top SST tube, centrifuge

Collect in tiger top SST tube, centrifuge


Serum separated from the clot can be maintained at refrigerated temperature (2-8°C) during transit for no more than four days after collection.  Serum separated from the clot can be aliquoted, stored frozen (-20°C or colder) and shipped with dry ice.

Acceptable Specimen Type(s)


Test Request

Possible Results

  • Reactive 
  • Nonreactive 
  • Unsatisfactory 

Reference Range


Unacceptable Conditions

  • Missing testing requisition  
  • Missing minimum of 2 patient identifiers 
  • Improper labeling 
  • Improper storage/transport of specimen 
  • No specimen received (empty collection tube). 
  • Wrong specimen type 
  • Specimen damaged, broken, or leaking upon arrival 

Interfering Substances


Result Reported

3-5 business days 

5-7 business days – Antigen positives 


Fee Schedule

LOINC/Order Codes

77190-7 (Order code: 1410)