Syphilis-Routine RPR Titer Only

Brief Description

RPR (Rapid Plasma Reagin) Card Test for Syphilis is a qualitative and semiquantitative Nontreponemal Flocculation Test for the detection of Reagin antibodies in human serum as a screening test for serological evidence of syphilis. RPR can be used to screen for syphilis as well as monitor treatment. 

Laboratory Unit

  • Immunology GPHL
  • Serology WPHL


RPR (Rapid Plasma Reagin) Card Test: Flocculation

Specimen Collection


Collect in gold top SST tube, centrifuge.

Collect in tiger top SST tube, centrifuge.


Serum separated from the clot can be maintained at refrigerated temperature (2-8°C) during transit for no more than five days after collection.

Serum separated from the clot can be stored frozen (-20°C or colder) and shipped with dry ice.

Acceptable Specimen Type(s)


Test Request

Possible Results

  • Titer: Endpoint (highest dilution giving a reactive result)
  • Unsatisfactory

Reference Range


Unacceptable Conditions

  • Plasma Specimens
  • Missing testing requisition
  • Missing minimum of 2 patient identifiers
  • Improper labeling
  • Improper storage/transport of specimen
  • No specimen received (empty collection tube).
  • Wrong specimen type
  • Specimens damaged, broken, or leaking upon arrival
  • Grossly hemolyzed or lipemic
  • Specimen broken or leaked in transit
  • Received more than 5 Days post collection

Interfering Substances

Hemolysis, lipemia, and bacterial contamination

Result Reported

3-5 business days


No charge

LOINC/Order Codes

20507-0 (Order code: 16101Decatur, W20300 Waycross)